FOXA3, a Negative Regulator of Nur77 Expression and Activity in Testicular Steroidogenesis

Biosynthesis of testosterone occurs mainly in the testicular Leydig cells. Nur77, an orphan nuclear receptor that is expressed in response to the luteinizing hormone/cyclic adenosine monophosphate (LH/cAMP) signaling pathway, is one of the key factors that regulate steroidogenesis in Leydig cells. T...

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Detalhes bibliográficos
Principais autores: Hansle Kim, Sudeep Kumar, Keesook Lee
Formato: Artigo
Idioma:English
Publicado em: Wiley 2021-01-01
coleção:International Journal of Endocrinology
Acesso em linha:http://dx.doi.org/10.1155/2021/6619447