The actual status of drug prices and adjustment factors for drug price calculation: an analysis of ultra-orphan drug development in Japan

Abstract Background Extremely high prices facilitate drug development for ultra-rare diseases (ultra-orphan drugs). However, various problems arise in terms of healthcare financing and fairness, and the status of ultra-orphan drug pricing remains ambiguous. In this study, we investigated ultra-orpha...

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Bibliographic Details
Main Authors: Akihiko Kawakami, Ken Masamune
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Online Access:https://doi.org/10.1186/s13023-022-02526-z