Celecoxib Inhibits the Lytic Activation of Kaposi’s Sarcoma-Associated Herpesvirus through Down-Regulation of RTA Expression by Inhibiting the Activation of p38 MAPK

Celecoxib Inhibits the Lytic Activation of Kaposi’s Sarcoma-Associated Herpesvirus through Down-Regulation of RTA Expression by Inhibiting the Activation of p38 MAPK

Kaposi’s sarcoma associated herpesvirus (KSHV) is the etiologic agent of Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). KSHV’s lytic replication cycle is critical for the pathogenesis of KSHV-associated diseases. Despite recent progress in the de...

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Bibliographic Details
Main Authors: Jungang Chen, Liangyu Jiang, Ke Lan, Xulin Chen
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Viruses
Subjects:
Kaposi’s sarcoma associated herpesvirus
celecoxib
RTA
p38 MAPK
Online Access:http://www.mdpi.com/1999-4915/7/5/2268

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http://www.mdpi.com/1999-4915/7/5/2268

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