Study of the anticancer effect of new quinazolinone hydrazine derivatives as receptor tyrosine kinase inhibitors

Study of the anticancer effect of new quinazolinone hydrazine derivatives as receptor tyrosine kinase inhibitors

The advent of novel receptor tyrosine kinase inhibitors has provided an important therapeutic tool for cancer patients. In this study, a series of quinazolinone hydrazide triazole derivatives were designed and synthesized as novel MET (c-MET) receptor tyrosine kinase inhibitors. The antiproliferativ...

Descripción completa

Detalles Bibliográficos
Autores principales: Motahareh Mortazavi, Masoumeh Divar, Tahereh Damghani, Fatemeh Moosavi, Luciano Saso, Somayeh Pirhadi, Mehdi Khoshneviszadeh, Najmeh Edraki, Omidreza Firuzi
Formato: Artículo
Lenguaje:English
Publicado: Frontiers Media S.A. 2022-11-01
Colección:Frontiers in Chemistry
Materias:
anticancer agents
kinase inhibitors
multitargeted compounds
drug design
three-dimensional culture
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fchem.2022.969559/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.969559/full

Ejemplares similares