S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse.

S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse.

Treatment of chronic hepatitis C (CHC) with pegylated interferon α (pegIFNα) and ribavirin results in a sustained response in approximately half of patients. Viral interference with IFNα signal transduction through the Jak-STAT pathway might be an important factor underlying treatment failure. S-ade...

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Bibliographic Details
Main Authors: Magdalena Filipowicz, Christine Bernsmeier, Luigi Terracciano, Francois H T Duong, Markus H Heim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2975710?pdf=render

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http://europepmc.org/articles/PMC2975710?pdf=render

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