BMP signaling alters aquaporin-4 expression in the mouse cerebral cortex

BMP signaling alters aquaporin-4 expression in the mouse cerebral cortex

Abstract Aquaporin-4 (AQP4) is a predominant water channel expressed in astrocytes in the mammalian brain. AQP4 is crucial for the regulation of homeostatic water movement across the blood–brain barrier (BBB). Although the molecular mechanisms regulating AQP4 levels in the cerebral cortex under path...

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Bibliographic Details
Main Authors: Kazuya Morita, Naoyuki Matsumoto, Kengo Saito, Toshihide Hamabe-Horiike, Keishi Mizuguchi, Yohei Shinmyo, Hiroshi Kawasaki
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89997-5

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https://doi.org/10.1038/s41598-021-89997-5

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