ZIC2 and ZIC3 promote SWI/SNF recruitment to safeguard progression towards human primed pluripotency

ZIC2 and ZIC3 promote SWI/SNF recruitment to safeguard progression towards human primed pluripotency

Abstract The primed epiblast acts as a transitional stage between the relatively homogeneous naïve epiblast and the gastrulating embryo. Its formation entails coordinated changes in regulatory circuits driven by transcription factors and epigenetic modifications. Using a multi-omic approach in human...

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Main Authors: Ishtiaque Hossain, Pierre Priam, Sofia C. Reynoso, Sahil Sahni, Xiao X. Zhang, Laurence Côté, Joelle Doumat, Candus Chik, Tianxin Fu, Julie A. Lessard, William A. Pastor
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52431-1

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https://doi.org/10.1038/s41467-024-52431-1

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