Expression of <i>E. coli</i> FimH Enhances Trafficking of an Orally Delivered <i>Lactobacillus acidophilus</i> Vaccine to Immune Inductive Sites via Antigen-Presenting Cells

Expression of <i>E. coli</i> FimH Enhances Trafficking of an Orally Delivered <i>Lactobacillus acidophilus</i> Vaccine to Immune Inductive Sites via Antigen-Presenting Cells

The development of lactic acid bacteria as mucosal vaccine vectors requires the identification of robust mucosal adjuvants to increase vaccine effectiveness. The <i>E. coli</i> type I fimbriae adhesion protein FimH is of interest as a mucosal adjuvant as it targets microfold (M) cells en...

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Bibliographic Details
Main Authors: Allison C. Vilander, Kimberly Shelton, Alora LaVoy, Gregg A. Dean
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Vaccines
Subjects:
mucosal vaccines
adjuvant
FimH
lactic acid bacteria
<i>Lactobacillus acidophilus</i>
Online Access:https://www.mdpi.com/2076-393X/11/7/1162

Internet

https://www.mdpi.com/2076-393X/11/7/1162

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