HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4

<p>Abstract</p> <p>Background</p> <p>Cell-to-cell HIV transmission requires cellular contacts that may be in part mediated by the integrin leukocyte function antigen (LFA)-1 and its ligands intercellular adhesion molecule (ICAM)-1, -2 and -3. The role of these molecules...

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Bibliographic Details
Main Authors: Juan Manel, Martinez-Picado Javier, Bofill Margarita, Curriu Marta, Ruiz-Hernandez Raul, Izquierdo-Useros Nuria, Massanella Marta, Puigdomènech Isabel, Clotet Bonaventura, Blanco Julià
Format: Article
Language:English
Published: BMC 2008-03-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/32