Migratory chondroprogenitors retain superior intrinsic chondrogenic potential for regenerative cartilage repair as compared to human fibronectin derived chondroprogenitors

Abstract Cell-based therapy for articular hyaline cartilage regeneration predominantly involves the use of mesenchymal stem cells and chondrocytes. However, the regenerated repair tissue is suboptimal due to the formation of mixed hyaline and fibrocartilage, resulting in inferior long-term functiona...

Full description

Bibliographic Details
Main Authors: Elizabeth Vinod, Noel Naveen Johnson, Sanjay Kumar, Soosai Manickam Amirtham, Jithu Varghese James, Abel Livingston, Grace Rebekah, Alfred Job Daniel, Boopalan Ramasamy, Solomon Sathishkumar
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-03082-5