Alzheimer's disease biomarker discovery using <it>in silico</it> literature mining and clinical validation

Alzheimer's disease biomarker discovery using <it>in silico</it> literature mining and clinical validation

<p>Abstract</p> <p>Background</p> <p>Alzheimer’s Disease (AD) is the most widespread form of dementia in the elderly but despite progress made in recent years towards a mechanistic understanding, there is still an urgent need for disease modification therapy and for ear...

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Bibliographic Details
Main Authors: Greco Ines, Day Nicola, Riddoch-Contreras Joanna, Reed Jane, Soininen Hilkka, Kłoszewska Iwona, Tsolaki Magda, Vellas Bruno, Spenger Christian, Mecocci Patrizia, Wahlund Lars-Olof, Simmons Andrew, Barnes Julie, Lovestone Simon
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Journal of Translational Medicine
Subjects:
Alzheimer’s disease
Proteomics
Biomarkers
Choline acetyltransferase (ChAt)
Urokinase-type plasminogen activator receptor (PLAUR)
Intelligence network
Bioinformatics
MRI
<it>in silico</it>
Literature mining
Online Access:http://www.translational-medicine.com/content/10/1/217

Internet

http://www.translational-medicine.com/content/10/1/217

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