Estradiol mediates colonic epithelial protection in aged mice after stroke and is associated with shifts in the gut microbiome

ABSTRACTThe gut is a major source of bacteria and antigens that contribute to neuroinflammation after brain injury. Colonic epithelial cells (ECs) are responsible for secreting major cellular components of the innate defense system, including antimicrobial proteins (AMP) and mucins. These cells serv...

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Bibliographic Details
Main Authors: Juneyoung Lee, Pedram Peesh, Victoria Quaicoe, Chunfeng Tan, Anik Banerjee, Patrick Mooz, Bhanu P. Ganesh, Joseph Petrosino, Robert M. Bryan, Louise D. McCullough, Venugopal Reddy Venna
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2271629