Endothelial cell activation mediated by cold ischemia-released mitochondria is partially inhibited by defibrotide and impacts on early allograft function following liver transplantation

Endothelial cell activation mediated by cold ischemia-released mitochondria is partially inhibited by defibrotide and impacts on early allograft function following liver transplantation

DAMPs (danger-associated molecular patterns) are self-molecules of the organism that appear after damage. The endothelium plays several roles in organ rejection, such as presenting alloantigens to T cells and contributing to the development of inflammation and thrombosis. This study aimed to assess...

Full description

Bibliographic Details
Main Authors: Francisco Villalba-López, David García-Bernal, Sandra V. Mateo, Daniel Vidal-Correoso, Marta Jover-Aguilar, Felipe Alconchel, Laura Martínez-Alarcón, Víctor López-López, Antonio Ríos-Zambudio, Pedro Cascales, José A. Pons, Pablo Ramírez, Pablo Pelegrín, Alberto Baroja-Mazo
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Endothelial cells
Mitochondria
Liver transplant
Cold ischemia
Defibrotide
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223013276

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223013276

Similar Items