Structural Insights into the Interactions of Digoxin and Na<sup>+</sup>/K<sup>+</sup>-ATPase and Other Targets for the Inhibition of Cancer Cell Proliferation

Digoxin is a cardiac glycoside long used to treat congestive heart failure and found recently to show antitumor potential. The hydroxy groups connected at the C-12, C-14, and C-3′a positions; the C-17 unsaturated lactone unit; the conformation of the steroid core; and the C-3 saccharide moiety have...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Yulin Ren, Sijin Wu, Joanna E. Burdette, Xiaolin Cheng, A. Douglas Kinghorn
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2021-06-01
Цуврал:Molecules
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/1420-3049/26/12/3672