A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells

A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells

Abstract Background Mantle cell lymphoma (MCL) is a rare, highly heterogeneous type of B-cell non-Hodgkin’s lymphoma. The sumoylation pathway is known to be upregulated in many cancers including lymphoid malignancies. However, little is known about its oncogenic role in MCL. Methods Levels of sumoyl...

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Bibliographic Details
Main Authors: Walter Hanel, Pushpa Lata, Youssef Youssef, Ha Tran, Liudmyla Tsyba, Lalit Sehgal, Bradley W. Blaser, Dennis Huszar, JoBeth Helmig-Mason, Liwen Zhang, Morgan S. Schrock, Matthew K. Summers, Wing Keung Chan, Alexander Prouty, Bethany L. Mundy-Bosse, Selina Chen-Kiang, Alexey V. Danilov, Kami Maddocks, Robert A. Baiocchi, Lapo Alinari
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Experimental Hematology & Oncology
Subjects:
UBA2
SAE1
SAE2
UBC9
UBE2I
Topoisomerase
Online Access:https://doi.org/10.1186/s40164-022-00293-y

Internet

https://doi.org/10.1186/s40164-022-00293-y

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