Blocking of inflammatory heparan sulfate domains by specific antibodies is not protective in experimental glomerulonephritis.

Glomerulonephritis is an acquired serious glomerular disease, which involves the interplay of many factors such as cytokines, chemokines, inflammatory cells, and heparan sulfate (HS). We previously showed that blocking of inflammatory heparan sulfate domains on cultured glomerular endothelium by spe...

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Bibliographic Details
Main Authors: Jasper J van Gemst, Nathalie J H G Passmann, Angelique L W M M Rops, Toin H van Kuppevelt, Jo H Berden, Markus A Loeven, Ton J Rabelink, Bart Smeets, Johan van der Vlag
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0261722