Transdermal influenza immunization with vaccine-coated microneedle arrays.

Influenza is a contagious disease caused by a pathogenic virus, with outbreaks all over the world and thousands of hospitalizations and deaths every year. Due to virus antigenic drift and short-lived immune responses, annual vaccination is required. However, vaccine coverage is incomplete, and impro...

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Bibliographic Details
Main Authors: Dimitrios G Koutsonanos, Maria del Pilar Martin, Vladimir G Zarnitsyn, Sean P Sullivan, Richard W Compans, Mark R Prausnitz, Ioanna Skountzou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2651574?pdf=render