<i>Atg4b</i> Overexpression Extends Lifespan and Healthspan in <i>Drosophila melanogaster</i>

Autophagy plays important but complex roles in aging, affecting health and longevity. We found that, in the general population, the levels of <i>ATG4B</i> and <i>ATG4D</i> decreased during aging, yet they are upregulated in centenarians, suggesting that overexpression of ATG4...

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Bibliographic Details
Main Authors: Yongxuan Li, Wei Zhang, Yunshuang Ye, Yinan Sun, Liping Yang, Guijun Chen, Kangning Chen, Sheryl Smith, Jumin Zhou
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/12/9893