Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos

Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos

Summary: DNA accessibility of cis-regulatory elements (CREs) dictates transcriptional activity and drives cell differentiation during development. While many genes regulating embryonic development have been identified, the underlying CRE dynamics controlling their expression remain largely uncharact...

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Bibliographic Details
Main Authors: Alison C. McGarvey, Wolfgang Kopp, Dubravka Vučićević, Kenny Mattonet, Rieke Kempfer, Antje Hirsekorn, Ilija Bilić, Marine Gil, Alexandra Trinks, Anne Margarete Merks, Daniela Panáková, Ana Pombo, Altuna Akalin, Jan Philipp Junker, Didier Y.R. Stainier, David Garfield, Uwe Ohler, Scott Allen Lacadie
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cell Genomics
Subjects:
zebrafish
chromatin
cis regulatory element
enhancer
promoter
single-cell ATAC-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S2666979X2100104X

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http://www.sciencedirect.com/science/article/pii/S2666979X2100104X

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