REST and CoREST modulate neuronal subtype specification, maturation and maintenance.

The repressor element-1 silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) is a master regulator of neuronal gene expression. REST functions as a modular scaffold for dynamic recruitment of epigenetic regulatory factors including its primary cofactor, the corepressor for e...

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Bibliographic Details
Main Authors: Joseph J Abrajano, Irfan A Qureshi, Solen Gokhan, Deyou Zheng, Aviv Bergman, Mark F Mehler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2782136?pdf=render