Aspergillus fumigatus Elongator complex subunit 3 affects hyphal growth, adhesion and virulence through wobble uridine tRNA modification.

The eukaryotic multisubunit Elongator complex has been shown to perform multiple functions in transcriptional elongation, histone acetylation and tRNA modification. However, the Elongator complex plays different roles in different organisms, and the underlying mechanisms remain unexplored. Moreover,...

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Bibliographic Details
Main Authors: Yuanwei Zhang, Yamei Wang, Jialu Fan, Guoxing Zhu, Ling Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010976