Negative Impact of Comorbidity on Health-Related Quality of Life Among Patients With Stroke as Modified by Good Diet Quality
BackgroundComorbidity, along with aging, affects stroke-induced health-related quality of life (HRQoL). We examined the potential role of diet quality in modifying the association between comorbidity and HRQoL in patients with stroke.MethodsA cross-sectional study was conducted on 951 patients with...
Main Authors: | , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-05-01
|
Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.836027/full |
_version_ | 1818544572245999616 |
---|---|
author | Thu T. M. Pham Thu T. M. Pham Manh-Tan Vu Manh-Tan Vu Thuc C. Luong Thuc C. Luong Khue M. Pham Khue M. Pham Lien T. K. Nguyen Lien T. K. Nguyen Lien T. K. Nguyen Minh H. Nguyen Binh N. Do Binh N. Do Hoang C. Nguyen Hoang C. Nguyen Tuan V. Tran Tuan V. Tran Thao T. P. Nguyen Hoang P. Le Cuong Q. Tran Cuong Q. Tran Kien T. Nguyen Shwu-Huey Yang Shwu-Huey Yang Shwu-Huey Yang Chaur-Jong Hu Chaur-Jong Hu Chyi-Huey Bai Chyi-Huey Bai Chyi-Huey Bai Tuyen Van Duong |
author_facet | Thu T. M. Pham Thu T. M. Pham Manh-Tan Vu Manh-Tan Vu Thuc C. Luong Thuc C. Luong Khue M. Pham Khue M. Pham Lien T. K. Nguyen Lien T. K. Nguyen Lien T. K. Nguyen Minh H. Nguyen Binh N. Do Binh N. Do Hoang C. Nguyen Hoang C. Nguyen Tuan V. Tran Tuan V. Tran Thao T. P. Nguyen Hoang P. Le Cuong Q. Tran Cuong Q. Tran Kien T. Nguyen Shwu-Huey Yang Shwu-Huey Yang Shwu-Huey Yang Chaur-Jong Hu Chaur-Jong Hu Chyi-Huey Bai Chyi-Huey Bai Chyi-Huey Bai Tuyen Van Duong |
author_sort | Thu T. M. Pham |
collection | DOAJ |
description | BackgroundComorbidity, along with aging, affects stroke-induced health-related quality of life (HRQoL). We examined the potential role of diet quality in modifying the association between comorbidity and HRQoL in patients with stroke.MethodsA cross-sectional study was conducted on 951 patients with stroke from December 2019 to December 2020 across Vietnam. Comorbidity was assessed using the Charlson Comorbidity Index (CCI) items and classified into two groups (none vs. one or more). Diet quality was evaluated using the Dietary Approaches to Stop Hypertension Quality (DASH-Q) questionnaire, and HRQoL was measured using the RAND-36, with a higher score indicating better diet quality or HRQoL, respectively. Besides, socio-demographics, health-related behaviors (e.g., physical activity, smoking, and drinking), disability (using WHODAS 2.0), and health literacy were also assessed. Linear regression analysis was utilized to explore the associations and interactions.ResultsThe proportion of patients with stroke aged ≥65 years and having comorbidity were 53.7 and 49.9%, respectively. The HRQoL scores were 44.4 ± 17.4. The diet quality was associated with higher HRQoL score (regression coefficient, B, 0.14; (95% confidence interval, 95% CI, 0.04, 0.23; p = 0.004), whereas comorbidity was associated with lower HRQoL score (B, −7.36; 95% CI, −9.50, −5.23; p < 0.001). In interaction analysis, compared to patients without comorbidity and having the lowest DASH-Q score, those with comorbidity and higher DASH-Q score had a higher HRQoL score (B, 0.21; 95% CI, 0.03, 0.39; p = 0.021).ConclusionThe findings showed that good diet quality could modify the adverse impact of comorbidity on HRQoL in patients with stroke. Diet quality should be considered as a strategic intervention to improve the HRQoL of patients with stroke, especially those with comorbidity, and to promote healthier aging. |
first_indexed | 2024-12-11T22:50:15Z |
format | Article |
id | doaj.art-cf39d5e7f6de422d8aada94918cc87e9 |
institution | Directory Open Access Journal |
issn | 2296-858X |
language | English |
last_indexed | 2024-12-11T22:50:15Z |
publishDate | 2022-05-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Medicine |
spelling | doaj.art-cf39d5e7f6de422d8aada94918cc87e92022-12-22T00:47:28ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-05-01910.3389/fmed.2022.836027836027Negative Impact of Comorbidity on Health-Related Quality of Life Among Patients With Stroke as Modified by Good Diet QualityThu T. M. Pham0Thu T. M. Pham1Manh-Tan Vu2Manh-Tan Vu3Thuc C. Luong4Thuc C. Luong5Khue M. Pham6Khue M. Pham7Lien T. K. Nguyen8Lien T. K. Nguyen9Lien T. K. Nguyen10Minh H. Nguyen11Binh N. Do12Binh N. Do13Hoang C. Nguyen14Hoang C. Nguyen15Tuan V. Tran16Tuan V. Tran17Thao T. P. Nguyen18Hoang P. Le19Cuong Q. Tran20Cuong Q. Tran21Kien T. Nguyen22Shwu-Huey Yang23Shwu-Huey Yang24Shwu-Huey Yang25Chaur-Jong Hu26Chaur-Jong Hu27Chyi-Huey Bai28Chyi-Huey Bai29Chyi-Huey Bai30Tuyen Van Duong31School of Public Health, College of Public Health, Taipei Medical University, Taipei, TaiwanFaculty of Public Health, Hai Phong University of Medicine and Pharmacy, Hai Phong, VietnamDepartment of Internal Medicine, Hai Phong University of Medicine and Pharmacy, Hai Phong, VietnamCardiovascular Department, Viet Tiep Friendship Hospital, Hai Phong, VietnamDirector Office, Military Hospital 103, Hanoi, VietnamCardiovascular Center, Department of Cardiology, Military Hospital 103, Hanoi, VietnamFaculty of Public Health, Hai Phong University of Medicine and Pharmacy, Hai Phong, VietnamPresident Office, Hai Phong University of Medicine and Pharmacy, Hai Phong, VietnamRehabilitation Department, Hanoi Medical University, Hanoi, Vietnam0Rehabilitation Center, Bach Mai Hospital, Hanoi, Vietnam1Rehabilitation Department, Viet Duc University Hospital, Hanoi, Vietnam2International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan3Department of Infectious Diseases, Vietnam Military Medical University, Hanoi, Vietnam4Division of Military Science, Military Hospital 103, Hanoi, Vietnam5Director Office, Thai Nguyen National Hospital, Thái Nguyên, Vietnam6President Office, Thai Nguyen University of Medicine and Pharmacy, Thái Nguyên, Vietnam7Department of Neurology, Thai Nguyen University of Medicine and Pharmacy, Thái Nguyên, Vietnam8Department of Clinical Pharmacy, Thai Nguyen University of Medicine and Pharmacy, Thái Nguyên, Vietnam9Health Personnel Training Institute, University of Medicine and Pharmacy, Hue University, Hue, Vietnam0Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam1Director Office, Thu Duc City Health Center, Ho Chi Minh City, Vietnam2Faculty of Health Sciences, Mekong University, Vl̃nh Long, Vietnam3Department of Health Promotion, Faculty of Social and Behavioral Sciences, Hanoi University of Public Health, Hanoi, Vietnam4School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan5Nutrition Research Center, Taipei Medical University Hospital, Taipei, Taiwan6Research Center of Geriatric Nutrition, Taipei Medical University, Taipei, Taiwan7Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan8Department of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanSchool of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan2International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan9Department of Public Health, College of Medicine, Taipei Medical University, Taipei, Taiwan4School of Nutrition and Health Sciences, Taipei Medical University, Taipei, TaiwanBackgroundComorbidity, along with aging, affects stroke-induced health-related quality of life (HRQoL). We examined the potential role of diet quality in modifying the association between comorbidity and HRQoL in patients with stroke.MethodsA cross-sectional study was conducted on 951 patients with stroke from December 2019 to December 2020 across Vietnam. Comorbidity was assessed using the Charlson Comorbidity Index (CCI) items and classified into two groups (none vs. one or more). Diet quality was evaluated using the Dietary Approaches to Stop Hypertension Quality (DASH-Q) questionnaire, and HRQoL was measured using the RAND-36, with a higher score indicating better diet quality or HRQoL, respectively. Besides, socio-demographics, health-related behaviors (e.g., physical activity, smoking, and drinking), disability (using WHODAS 2.0), and health literacy were also assessed. Linear regression analysis was utilized to explore the associations and interactions.ResultsThe proportion of patients with stroke aged ≥65 years and having comorbidity were 53.7 and 49.9%, respectively. The HRQoL scores were 44.4 ± 17.4. The diet quality was associated with higher HRQoL score (regression coefficient, B, 0.14; (95% confidence interval, 95% CI, 0.04, 0.23; p = 0.004), whereas comorbidity was associated with lower HRQoL score (B, −7.36; 95% CI, −9.50, −5.23; p < 0.001). In interaction analysis, compared to patients without comorbidity and having the lowest DASH-Q score, those with comorbidity and higher DASH-Q score had a higher HRQoL score (B, 0.21; 95% CI, 0.03, 0.39; p = 0.021).ConclusionThe findings showed that good diet quality could modify the adverse impact of comorbidity on HRQoL in patients with stroke. Diet quality should be considered as a strategic intervention to improve the HRQoL of patients with stroke, especially those with comorbidity, and to promote healthier aging.https://www.frontiersin.org/articles/10.3389/fmed.2022.836027/fullstrokecomorbiditydietmodificationhealth-related quality of lifeaging |
spellingShingle | Thu T. M. Pham Thu T. M. Pham Manh-Tan Vu Manh-Tan Vu Thuc C. Luong Thuc C. Luong Khue M. Pham Khue M. Pham Lien T. K. Nguyen Lien T. K. Nguyen Lien T. K. Nguyen Minh H. Nguyen Binh N. Do Binh N. Do Hoang C. Nguyen Hoang C. Nguyen Tuan V. Tran Tuan V. Tran Thao T. P. Nguyen Hoang P. Le Cuong Q. Tran Cuong Q. Tran Kien T. Nguyen Shwu-Huey Yang Shwu-Huey Yang Shwu-Huey Yang Chaur-Jong Hu Chaur-Jong Hu Chyi-Huey Bai Chyi-Huey Bai Chyi-Huey Bai Tuyen Van Duong Negative Impact of Comorbidity on Health-Related Quality of Life Among Patients With Stroke as Modified by Good Diet Quality Frontiers in Medicine stroke comorbidity diet modification health-related quality of life aging |
title | Negative Impact of Comorbidity on Health-Related Quality of Life Among Patients With Stroke as Modified by Good Diet Quality |
title_full | Negative Impact of Comorbidity on Health-Related Quality of Life Among Patients With Stroke as Modified by Good Diet Quality |
title_fullStr | Negative Impact of Comorbidity on Health-Related Quality of Life Among Patients With Stroke as Modified by Good Diet Quality |
title_full_unstemmed | Negative Impact of Comorbidity on Health-Related Quality of Life Among Patients With Stroke as Modified by Good Diet Quality |
title_short | Negative Impact of Comorbidity on Health-Related Quality of Life Among Patients With Stroke as Modified by Good Diet Quality |
title_sort | negative impact of comorbidity on health related quality of life among patients with stroke as modified by good diet quality |
topic | stroke comorbidity diet modification health-related quality of life aging |
url | https://www.frontiersin.org/articles/10.3389/fmed.2022.836027/full |
work_keys_str_mv | AT thutmpham negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT thutmpham negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT manhtanvu negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT manhtanvu negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT thuccluong negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT thuccluong negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT khuempham negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT khuempham negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT lientknguyen negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT lientknguyen negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT lientknguyen negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT minhhnguyen negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT binhndo negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT binhndo negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT hoangcnguyen negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT hoangcnguyen negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT tuanvtran negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT tuanvtran negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT thaotpnguyen negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT hoangple negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT cuongqtran negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT cuongqtran negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT kientnguyen negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT shwuhueyyang negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT shwuhueyyang negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT shwuhueyyang negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT chaurjonghu negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT chaurjonghu negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT chyihueybai negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT chyihueybai negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT chyihueybai negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality AT tuyenvanduong negativeimpactofcomorbidityonhealthrelatedqualityoflifeamongpatientswithstrokeasmodifiedbygooddietquality |