Structural dynamics of the CROPs domain control stability and toxicity of Paeniclostridium sordellii lethal toxin

Structural dynamics of the CROPs domain control stability and toxicity of Paeniclostridium sordellii lethal toxin

Abstract Paeniclostridium sordellii lethal toxin (TcsL) is a potent exotoxin that causes lethal toxic shock syndrome associated with fulminant bacterial infections. TcsL belongs to the large clostridial toxin (LCT) family. Here, we report that TcsL with varied lengths of combined repetitive oligopep...

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Bibliographic Details
Main Authors: Yao Zhou, Xiechao Zhan, Jianhua Luo, Diyin Li, Ruoyu Zhou, Jiahao Zhang, Zhenrui Pan, Yuanyuan Zhang, Tianhui Jia, Xiaofeng Zhang, Yanyan Li, Liang Tao
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44169-z

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https://doi.org/10.1038/s41467-023-44169-z

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