In vitro hepatic biotransformation of the algal toxin pectenotoxin-2

In vitro hepatic biotransformation of the algal toxin pectenotoxin-2

We have investigated the in vitro metabolism of pectenotoxin-2 (PTX-2) using primary hepatocytes from Wistar rats in suspension. Purified PTX-2 was rapidly metabolized. Two major and several minor oxidized PTX-2 metabolites were formed, none of which had retention times corresponding to PTX-1, -11,...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Morten Sandvik, Christopher O. Miles, Alistair L. Wilkins, Christiane Fæste
Formáid:	Alt
Teanga:	English
Foilsithe / Cruthaithe:	Elsevier 2020-06-01
Sraith:	Toxicon: X
Rochtain ar líne:	http://www.sciencedirect.com/science/article/pii/S2590171020300096

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