In vitro hepatic biotransformation of the algal toxin pectenotoxin-2

In vitro hepatic biotransformation of the algal toxin pectenotoxin-2

We have investigated the in vitro metabolism of pectenotoxin-2 (PTX-2) using primary hepatocytes from Wistar rats in suspension. Purified PTX-2 was rapidly metabolized. Two major and several minor oxidized PTX-2 metabolites were formed, none of which had retention times corresponding to PTX-1, -11,...

書目詳細資料
Main Authors:	Morten Sandvik, Christopher O. Miles, Alistair L. Wilkins, Christiane Fæste
格式:	Article
語言:	English
出版:	Elsevier 2020-06-01
叢編:	Toxicon: X
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2590171020300096

相似書籍

In Vitro Toxicokinetics and Phase I Biotransformation of the Mycotoxin Penitrem A in Dogs
由: Silvio Uhlig, et al.
出版: (2020-05-01)

Towards the total synthesis of pectenotoxin-4
由: Kwok, T
出版: (2020)

Synthesis of the ABC fragment of pectenotoxin-4
由: Lipinski, RM
出版: (2012)

Atlantic Salmon Gill Epithelial Cell Line (ASG-10) as a Suitable Model for Xenobiotic Biotransformation
由: Lada Ivanova, et al.
出版: (2023-06-01)

Synthesis of the EFG-ring system of pectenotoxin-4
由: Roushanbakhti, A
出版: (2017)

Towards the synthesis of the ABC fragment of pectenotoxin-4
由: Yang, X
出版: (2016)

Towards the synthesis of the ABC fragment of Pectenotoxin-4
由: Yang, X
出版: (2016)

Oxidative cyclization approach to the synthesis of pectenotoxin-4
由: Lipinski, R, et al.
出版: (2011)

Synthesis of the CDE & EFG ring systems of pectenotoxin-4
由: Liu, Y
出版: (2016)

A novel approach to the synthesis of the FG fragment of pectenotoxin-4
由: Luscombe, KN
出版: (2012)

Report on the First Detection of Pectenotoxin-2, Spirolide-A and Their Derivatives in French Shellfish
由: Eric Abadie, et al.
出版: (2007-11-01)

Influence of Temperature on Growth and Production of Pectenotoxin-2 by a Monoclonal Culture of Dinophysis caudata
由: Leila Basti, et al.
出版: (2015-12-01)

Towards the total synthesis of pectenotoxin-4: synthesis of the CDE and F rings
由: Richardson, M
出版: (2018)

New evidence of pectenotoxins in farmed bivalve molluscs from Sardinia (Italy)
由: Alessandro G. Mudadu, et al.
出版: (2021-06-01)

Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent—A Review
由: Wun-Jae Kim, et al.
出版: (2011-11-01)

Risk Assessment of Pectenotoxins in New Zealand Bivalve Molluscan Shellfish, 2009–2019
由: Michael J. Boundy, et al.
出版: (2020-12-01)

Accumulation and Biotransformation of Dinophysis Toxins by the Surf Clam Mesodesma donacium
由: Juan Blanco, et al.
出版: (2018-08-01)

Investigation of Pectenotoxin Profiles in the Yellow Sea (China) Using a Passive Sampling Technique
由: Zhaoxin Li, et al.
出版: (2010-04-01)

Metabolism of pectenotoxins in brown crabs Cancer pagurus fed blue mussels Mytilus edulis
由: Li Zhaoxin
出版: (2008-01-01)

Freshwater Algal Toxins: Monitoring and Toxicity Profile
由: Angeles Jos, et al.
出版: (2020-10-01)

Algal toxins alter copepod feeding behavior.
由: Jiarong Hong, et al.
出版: (2012-01-01)

Novel synthetic routes towards trans-THFs and application towards the FG fragment of pectenotoxin-4
由: Tucker, MJ
出版: (2013)

358 In Vitro Uptake of Harmful Algal Bloom Toxin Microcystin-LR in Human Placental Cells
由: Michael Campbell, et al.
出版: (2024-04-01)

Reservoir management strategies for control and degradation of algal toxins /
由: Brookes, Justin D., et al.
出版: (2009)

Interplay of cascade oxidative cyclization and hydride shifts in the synthesis of the ABC spiroketal ring system of pectenotoxin-4.
由: Donohoe, T, et al.
出版: (2013)

Cobalt versus osmium: control of both trans and cis selectivity in construction of the EFG rings of pectenotoxin 4
由: Roushanbakhti, A, et al.
出版: (2017)

Assimilation, Accumulation, and Metabolism of Dinophysistoxins (DTXs) and Pectenotoxins (PTXs) in the Several Tissues of Japanese Scallop Patinopecten yessoensis
由: Ryoji Matsushima, et al.
出版: (2015-12-01)

Identification of Biotransformation Products of T-2 Toxin in HepG2 Cells Using LC-Q-TOF MS
由: Mercedes Taroncher, et al.
出版: (2024-05-01)

Dissolved Algal Toxins along the Southern Coast of British Columbia Canada
由: Ryan B. Shartau, et al.
出版: (2023-06-01)

Cephalopods as Vectors of Harmful Algal Bloom Toxins in Marine Food Webs
由: Rui Rosa, et al.
出版: (2013-09-01)

Biotransformations /
由: Faber, K. (Kurt), 1953-
出版: (2000)

Opportunities in biotransformations /
由: Copping, L. G., et al.
出版: (1990)

Novel Microfluidic Analytical Sensing Platform for the Simultaneous Detection of Three Algal Toxins in Water
由: Ivan Maguire, et al.
出版: (2018-06-01)

Biotransformations: a survey of the biotransformation of drugs and chemicals in animals/
由: Hawkins, D. R.
出版: (1991)

Biotransformations a survey of the biotransformation of drugs and chemicals in animals /
由: Hawkins, D. R.
出版: (1988)

Harmful algal and cyanobacterial toxins in foraging green turtles (Chelonia mydas) in Florida's Big Bend
由: Justin R. Perrault, et al.
出版: (2020-03-01)

Industrial biotransformations /
由: Liese, A.
出版: (2000)

Industrial biotransformations /
由: Liese, A. (Andreas), et al.
出版: (2006)

Biocatalysis and biotransformation
出版: (19--)

Biotransformations and bioprocesses /
由: 175970 Doble, Mukesh, et al.
出版: (2004)