In vitro hepatic biotransformation of the algal toxin pectenotoxin-2
We have investigated the in vitro metabolism of pectenotoxin-2 (PTX-2) using primary hepatocytes from Wistar rats in suspension. Purified PTX-2 was rapidly metabolized. Two major and several minor oxidized PTX-2 metabolites were formed, none of which had retention times corresponding to PTX-1, -11,...
| Автори: | , , , |
|---|---|
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Elsevier
2020-06-01
|
| Серія: | Toxicon: X |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S2590171020300096 |