Research landscape of exosomes in platelets from 2000 to 2022: A bibliometric analysis

BackgroundBlood-derived exosomes are involved in developing multiple pathological processes, with platelets being the most well-known source. Related studies have become an area of research with significant value and potential. However, no bibliometric studies in this field have yet been identified....

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Main Authors: Min Zhan, Shengnan Shi, Xiaoyu Zheng, Wenjie Chen, Linjuan Sun, Yehao Zhang, Jianxun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1054816/full
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author Min Zhan
Min Zhan
Shengnan Shi
Xiaoyu Zheng
Xiaoyu Zheng
Wenjie Chen
Wenjie Chen
Linjuan Sun
Yehao Zhang
Jianxun Liu
author_facet Min Zhan
Min Zhan
Shengnan Shi
Xiaoyu Zheng
Xiaoyu Zheng
Wenjie Chen
Wenjie Chen
Linjuan Sun
Yehao Zhang
Jianxun Liu
author_sort Min Zhan
collection DOAJ
description BackgroundBlood-derived exosomes are involved in developing multiple pathological processes, with platelets being the most well-known source. Related studies have become an area of research with significant value and potential. However, no bibliometric studies in this field have yet been identified. We aimed to analyze the hotspots and academic trends of platelet exosome research through bibliometric visualization to actively grasp the research base in this field and track its developmental orientation.MethodsFrom 2000 to 2022, we screened all relevant publications on platelet exosome-related research from the Web of Science database, generated knowledge maps using VOSviewer and CiteSpace software, and analyzed research trends in the field.ResultsA total of 722 articles were screened for inclusion based on the search strategy. The number of articles on exosome studies in platelets has expanded vastly. The USA and the People’s Republic of China contributed substantially among 69 countries or regions. Amsterdam University and Semmelweis University are the research institutions with the most publications. The most studied and co-cited journals were the International Journal of Molecular Sciences and the Journal of Extracellular Vesicles. We identified 4,598 authors, with Nieuwland Rienk having the highest number of articles and Bruno Stefania having the most cited publications. Keywords of great interest include “thrombosis,” “anti-inflammatory,” “anti-apoptosis,” “angiogenesis,” “microparticles,” “miRNAs,” “stem cells,” and “biomarkers,” which are key research areas for future development.ConclusionWe used bibliometric and visualization methods to identify hotspots and trends in platelet exosome research. Platelet exosome research is widely expanding. Future research will most likely focus on “thrombosis,” “anti-inflammatory,” “anti-apoptosis,” “angiogenesis,” “microparticles,” “miRNAs,” “stem cells,” and “biomarkers.”
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spelling doaj.art-cf3ab5cc89824980bfddbe73e5ece88c2022-12-22T04:42:07ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-12-01910.3389/fcvm.2022.10548161054816Research landscape of exosomes in platelets from 2000 to 2022: A bibliometric analysisMin Zhan0Min Zhan1Shengnan Shi2Xiaoyu Zheng3Xiaoyu Zheng4Wenjie Chen5Wenjie Chen6Linjuan Sun7Yehao Zhang8Jianxun Liu9Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaGraduate School, China Academy of Chinese Medical Sciences, Beijing, ChinaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaGraduate School, China Academy of Chinese Medical Sciences, Beijing, ChinaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaGraduate School, China Academy of Chinese Medical Sciences, Beijing, ChinaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaBackgroundBlood-derived exosomes are involved in developing multiple pathological processes, with platelets being the most well-known source. Related studies have become an area of research with significant value and potential. However, no bibliometric studies in this field have yet been identified. We aimed to analyze the hotspots and academic trends of platelet exosome research through bibliometric visualization to actively grasp the research base in this field and track its developmental orientation.MethodsFrom 2000 to 2022, we screened all relevant publications on platelet exosome-related research from the Web of Science database, generated knowledge maps using VOSviewer and CiteSpace software, and analyzed research trends in the field.ResultsA total of 722 articles were screened for inclusion based on the search strategy. The number of articles on exosome studies in platelets has expanded vastly. The USA and the People’s Republic of China contributed substantially among 69 countries or regions. Amsterdam University and Semmelweis University are the research institutions with the most publications. The most studied and co-cited journals were the International Journal of Molecular Sciences and the Journal of Extracellular Vesicles. We identified 4,598 authors, with Nieuwland Rienk having the highest number of articles and Bruno Stefania having the most cited publications. Keywords of great interest include “thrombosis,” “anti-inflammatory,” “anti-apoptosis,” “angiogenesis,” “microparticles,” “miRNAs,” “stem cells,” and “biomarkers,” which are key research areas for future development.ConclusionWe used bibliometric and visualization methods to identify hotspots and trends in platelet exosome research. Platelet exosome research is widely expanding. Future research will most likely focus on “thrombosis,” “anti-inflammatory,” “anti-apoptosis,” “angiogenesis,” “microparticles,” “miRNAs,” “stem cells,” and “biomarkers.”https://www.frontiersin.org/articles/10.3389/fcvm.2022.1054816/fullplateletsexosomesCiteSpaceVOSviewerbibliometrics
spellingShingle Min Zhan
Min Zhan
Shengnan Shi
Xiaoyu Zheng
Xiaoyu Zheng
Wenjie Chen
Wenjie Chen
Linjuan Sun
Yehao Zhang
Jianxun Liu
Research landscape of exosomes in platelets from 2000 to 2022: A bibliometric analysis
Frontiers in Cardiovascular Medicine
platelets
exosomes
CiteSpace
VOSviewer
bibliometrics
title Research landscape of exosomes in platelets from 2000 to 2022: A bibliometric analysis
title_full Research landscape of exosomes in platelets from 2000 to 2022: A bibliometric analysis
title_fullStr Research landscape of exosomes in platelets from 2000 to 2022: A bibliometric analysis
title_full_unstemmed Research landscape of exosomes in platelets from 2000 to 2022: A bibliometric analysis
title_short Research landscape of exosomes in platelets from 2000 to 2022: A bibliometric analysis
title_sort research landscape of exosomes in platelets from 2000 to 2022 a bibliometric analysis
topic platelets
exosomes
CiteSpace
VOSviewer
bibliometrics
url https://www.frontiersin.org/articles/10.3389/fcvm.2022.1054816/full
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