<named-content content-type="genus-species">Candida albicans</named-content> Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization

<named-content content-type="genus-species">Candida albicans</named-content> Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization

ABSTRACT Macrophages rely on phagosomal acidity to destroy engulfed microorganisms. To survive this hostile response, opportunistic fungi such as Candida albicans developed strategies to evade the acidic environment. C. albicans is polymorphic and able to convert from yeast to hyphae, and this trans...

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Bibliographic Details
Main Authors: Johannes Westman, Gary Moran, Selene Mogavero, Bernhard Hube, Sergio Grinstein
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
Candida albicans
candidalysin
ECE1
alkalinization
ammonia
dual-wavelength radiometric imaging
Online Access:https://journals.asm.org/doi/10.1128/mBio.01226-18

Internet

https://journals.asm.org/doi/10.1128/mBio.01226-18

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