Hypoxic condition enhances chondrogenesis in synovium-derived mesenchymal stem cells

Abstract Background The chondrogenic differentiation of mesenchymal stem cells (MSCs) is regulated by many factors, including oxygen tensions, growth factors, and cytokines. Evidences have suggested that low oxygen tension seems to be an important regulatory factor in the proliferation and chondroge...

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Bibliographic Details
Main Authors: Hyun Cheol Bae, Hee Jung Park, Sun Young Wang, Ha Ru Yang, Myung Chul Lee, Hyuk-Soo Han
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2018-09-01
Series:Biomaterials Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40824-018-0134-x