Mutational biases favor complexity increases in protein interaction networks after gene duplication
Abstract Biological systems can gain complexity over time. While some of these transitions are likely driven by natural selection, the extent to which they occur without providing an adaptive benefit is unknown. At the molecular level, one example is heteromeric complexes replacing homomeric ones fo...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2024-03-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/s44320-024-00030-z |