Purification of time-resolved insulin granules reveals proteomic and lipidomic changes during granule aging
Summary: Endocrine cells employ regulated exocytosis of secretory granules to secrete hormones and neurotransmitters. Secretory granule exocytosis depends on spatiotemporal variables such as proximity to the plasma membrane and age, with newly generated granules being preferentially released. Despit...
| Päätekijät: | , , , , , , , , , , , , , |
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| Aineistotyyppi: | Artikkeli |
| Kieli: | English |
| Julkaistu: |
Elsevier
2024-03-01
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| Sarja: | Cell Reports |
| Aiheet: | |
| Linkit: | http://www.sciencedirect.com/science/article/pii/S2211124724001645 |