Enhanced lactate accumulation upregulates PD‐L1 expression to delay neutrophil apoptosis in sepsis
Abstract Malfunction of neutrophil apoptosis and elevated serum lactate levels are the key cellular mechanism of immune suppressive status in septic patients. However, whether increased lactate affects apoptosis of neutrophils and aggravates sepsis development, and the molecular mechanism remain unk...
| Główni autorzy: | , , , , , , , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
Wiley
2024-02-01
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| Seria: | View |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1002/VIW.20230053 |