FGF-trapping hampers cancer stem-like cells in uveal melanoma

FGF-trapping hampers cancer stem-like cells in uveal melanoma

Abstract Background Cancer stem-like cells (CSCs) are a subpopulation of tumor cells responsible for tumor initiation, metastasis, chemoresistance, and relapse. Recently, CSCs have been identified in Uveal Melanoma (UM), which represents the most common primary tumor of the eye. UM is highly resista...

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Bibliographic Details
Main Authors: Alessandra Loda, Stefano Calza, Arianna Giacomini, Cosetta Ravelli, Adwaid Manu Krishna Chandran, Chiara Tobia, Giovanna Tabellini, Silvia Parolini, Francesco Semeraro, Roberto Ronca, Sara Rezzola
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cancer Cell International
Subjects:
Uveal melanoma
Cancer stem-like cells
FGF
FGF inhibitor
Online Access:https://doi.org/10.1186/s12935-023-02903-z

Internet

https://doi.org/10.1186/s12935-023-02903-z

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