Recognition of 7 genes signature (Cirrhosis Risk Score) in the diagnosed non-responders to DAAs therapy by intra-PBMCs nested HCV RNA PCR

Recognition of 7 genes signature (Cirrhosis Risk Score) in the diagnosed non-responders to DAAs therapy by intra-PBMCs nested HCV RNA PCR

Abstract Background and aims Predictors of chronic HCV response to oral antiviral therapy (OAT) are related to host genetic variations. Single nucleotide polymorphisms (SNP) and alleles variations of host genes in association with hepatic fibro-cirrhotic changes have a distinct role in OAT outcomes....

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Bibliographic Details
Main Authors: Al-Shazly Gaber Mohamed Galal, Reham M. Dawood, Mostafa K. El Awady, Yasser Mohamed Mohamed El-Dessouky, Mohamed Mahmoud Abdel-Halim Mahmoud, Mohamed Darwish Ahmed Abd Alla
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
CRS
DAAs
PBMCs PCR
HCV Relapse
Liver fibro-cirrhosis
Online Access:https://doi.org/10.1186/s43141-023-00544-3

Internet

https://doi.org/10.1186/s43141-023-00544-3

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