PUM1 Promotes Tumor Progression by Activating DEPTOR‐Meditated Glycolysis in Gastric Cancer

PUM1 Promotes Tumor Progression by Activating DEPTOR‐Meditated Glycolysis in Gastric Cancer

Abstract RNA‐binding proteins (RBPs) play essential roles in tumorigenesis and progression, but their functions in gastric cancer (GC) remain largely elusive. Here, it is reported that Pumilio 1 (PUM1), an RBP, induces metabolic reprogramming through post‐transcriptional regulation of DEP domain‐con...

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Bibliographic Details
Main Authors: Songcheng Yin, Huifang Liu, Zhijun Zhou, Xiaoyu Xu, Pengliang Wang, Wei Chen, Guofei Deng, Han Wang, Hong Yu, Liang Gu, Mingyu Huo, Min Li, Leli Zeng, Yulong He, Changhua Zhang
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Advanced Science
Subjects:
DEPTOR
gastric cancer
glycolysis
PI3K–Akt pathway
PUM1
Online Access:https://doi.org/10.1002/advs.202301190

Internet

https://doi.org/10.1002/advs.202301190

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