The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation

The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation

The development of CD1d-restricted invariant natural killer T (iNKT) cells, a population that is critical for both innate and adaptive immunity, is regulated by multiple transcription factors, but the molecular mechanisms underlying how the transcriptional activation of these factors are regulated d...

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Bibliographic Details
Main Authors: Yajun Wang, Chawon Yun, Beixue Gao, Yuanming Xu, Yana Zhang, Yiming Wang, Qingfei Kong, Fang Zhao, Chyung-Ru Wang, Sharon Y.R. Dent, Jian Wang, Xiangping Xu, Hua-Bin Li, Deyu Fang
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Cell Reports
Subjects:
GCN5
EGR2
acetylation
iNKT
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717308963

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http://www.sciencedirect.com/science/article/pii/S2211124717308963

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