<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Lsr2 Is a Global Transcriptional Regulator Required for Adaptation to Changing Oxygen Levels and Virulence

ABSTRACT To survive a dynamic host environment, Mycobacterium tuberculosis must endure a series of challenges, from reactive oxygen and nitrogen stress to drastic shifts in oxygen availability. The mycobacterial Lsr2 protein has been implicated in reactive oxygen defense via direct protection of DNA...

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Bibliographic Details
Main Authors: I. L. Bartek, L. K. Woolhiser, A. D. Baughn, R. J. Basaraba, W. R. Jacobs, A. J. Lenaerts, M. I. Voskuil
Format: Article
Language:English
Published: American Society for Microbiology 2014-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01106-14