Checkpoint Inhibitors and Engineered Cells: New Weapons for Natural Killer Cell Arsenal Against Hematological Malignancies

Natural killer (NK) cells represent one of the first lines of defense against malignant cells. NK cell activation and recognition are regulated by a balance between activating and inhibitory receptors, whose specific ligands can be upregulated on tumor cells surface and tumor microenvironment (TME)....

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Bibliographic Details
Main Authors: Massimo Giuliani, Alessandro Poggi
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/7/1578