Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma

Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma

Doxorubicin (Dox) is one of the most important first-line drugs used in osteosarcoma therapy. Multiple and not fully clarified mechanisms, however, determine resistance to Dox. With the aim of identifying new markers associated with Dox-resistance, we found a global up-regulation of small nucleolar...

Full description

Bibliographic Details
Main Authors: Martina Godel, Deborah Morena, Preeta Ananthanarayanan, Ilaria Buondonno, Giulio Ferrero, Claudia M. Hattinger, Federica Di Nicolantonio, Massimo Serra, Riccardo Taulli, Francesca Cordero, Chiara Riganti, Joanna Kopecka
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
osteosarcoma
doxorubicin
chemoresistance
small nucleolar RNAs
Online Access:https://www.mdpi.com/1422-0067/21/12/4500

Internet

https://www.mdpi.com/1422-0067/21/12/4500

Similar Items