Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents

AbstractSGK1 is a serine/threonine kinase involved in several neurodegenerative-related pathways such as apoptosis, neuroinflammation, ionic channel regulation, and autophagy, among others. Despite its potential role as a pharmacological target against this kind of diseases, there are no reported in...

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Bibliographic Details
Main Authors: Ines Maestro, Enrique Madruga, Patricia Boya, Ana Martínez
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2022.2153841