Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures.

Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures.

Adenosine is involved in several neurological and behavioral disorders including alcoholism. In cultured cell and animal studies, type 1 equilibrative nucleoside transporter (ENT1, slc29a1), which regulates adenosine levels, is known to regulate ethanol sensitivity and preference. Interestingly, in...

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Bibliographic Details
Main Authors: Jeong-Hyun Kim, Victor M Karpyak, Joanna M Biernacka, Hyung Wook Nam, Moonnoh R Lee, Ulrich W Preuss, Peter Zill, Gihyun Yoon, Colin Colby, David A Mrazek, Doo-Sup Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3026043?pdf=render

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http://europepmc.org/articles/PMC3026043?pdf=render

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