An analysis of sexual dimorphism in the tumor microenvironment of colorectal cancer

An analysis of sexual dimorphism in the tumor microenvironment of colorectal cancer

Women with colorectal cancer (CRC) have survival advantages over men, yet the underlying mechanisms are unclear. T cell infiltration within the CRC tumor microenvironment (TME) correlates strongly with survival. We hypothesized that women with CRC have increased T cell infiltration and differential...

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Bibliographic Details
Main Authors: Andrea E. Geddes, Anita L. Ray, Robert A. Nofchissey, Azadeh Esmaeili, Apryl Saunders, Dawn E. Bender, Maaz Khan, Sheeja Aravindan, Jared T. Ahrendsen, Min Li, Kar-Ming Fung, Muralidharan Jayaraman, Jingxuan Yang, Kristina K. Booth, Gary D. Dunn, Steven N. Carter, Katherine T. Morris
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
tumor microenvironment
sexual dimorphism
T cell
immunoscore
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.986103/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.986103/full

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