Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages

Summary: The extracellular matrix plays a key role in stem cell maintenance, expansion, and differentiation. Laminin, a basement membrane protein, is a widely used substrate for cell culture including the growth of human induced pluripotent stem cells (hiPSCs). Here, we show that different isoforms...

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Bibliographic Details
Main Authors: Shun Shibata, Ryuhei Hayashi, Toru Okubo, Yuji Kudo, Tomohiko Katayama, Yuki Ishikawa, Junko Toga, Emiko Yagi, Yoichi Honma, Andrew J. Quantock, Kiyotoshi Sekiguchi, Kohji Nishida
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718316085