Deep exploration of the immune infiltrate and outcome prediction in testicular cancer by quantitative multiplexed immunohistochemistry and gene expression profiling

Deep exploration of the immune infiltrate and outcome prediction in testicular cancer by quantitative multiplexed immunohistochemistry and gene expression profiling

Platinum-based chemotherapy is usually curative for patients with testicular germ cell tumors (TGCT), but a subset of patients experience disease progression and poor clinical outcomes. Here, we tested whether immune profiling of TGCT could identify novel prognostic markers and therapeutic targets f...

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Bibliographic Details
Main Authors: Peter J. Siska, Romany A. N. Johnpulle, Alice Zhou, Jennifer Bordeaux, Ju Young Kim, Bashar Dabbas, Naveen Dakappagari, Jeffrey C. Rathmell, W. Kimryn Rathmell, Alicia K. Morgans, Justin M. Balko, Douglas B. Johnson
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:OncoImmunology
Subjects:
immune
non-seminoma
pd-1/pd-l1
seminoma
testicular
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1305535

Internet

http://dx.doi.org/10.1080/2162402X.2017.1305535

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