An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload

An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload

Adipocyte iron overload is a maladaptation associated with obesity and insulin resistance. The objective of the current study was to determine whether and how adipose tissue macrophages (ATMs) regulate adipocyte iron concentrations and whether this is impacted by obesity. Using bone marrow-derived m...

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Bibliographic Details
Main Authors: Magdalene K. Ameka, William N. Beavers, Ciara M. Shaver, Lorraine B. Ware, Vern Eric Kerchberger, Kelly Q. Schoenfelt, Lili Sun, Tatsuki Koyama, Eric P. Skaar, Lev Becker, Alyssa H. Hasty
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
immunometabolism
polarization
obesity
iron
adipose tissue macrophage
Online Access:https://www.mdpi.com/1422-0067/23/13/7417

Internet

https://www.mdpi.com/1422-0067/23/13/7417

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