Urolithin A attenuates osteoclast differentiation and compensates for ovariectomy-induced bone loss in mice by inhibiting PI3K/AKT/mTOR signaling pathway

Urolithin A attenuates osteoclast differentiation and compensates for ovariectomy-induced bone loss in mice by inhibiting PI3K/AKT/mTOR signaling pathway

Backgrounds and purposes: Osteoporosis (OP) is a debilitating illness distinguished by a reduction in bone density and microstructure, which leads to fragility, fracture risk, and increased mortality, particularly in the elderly and postmenopausal women. Growing evidence suggests that various plant...

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Bibliographic Details
Main Authors: Wenyun Zhou, Weijun Zhou, Zibin Zhou, Yonghao Bi, Zhigao Zhou, Shaozhe Chen, Zihong Lin, Jiajie Ye, Gang Xie, Wenjie Liu, Dantao Xie, Zhen Lian, Ruiwu Zheng, Xianghua Hu, Xinjia Wang, Guixin Yuan, Guanfeng Yao
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Phytomedicine Plus
Subjects:
Osteoporosis
Osteoclasts
Urolithin A
Online Access:http://www.sciencedirect.com/science/article/pii/S266703132300091X

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http://www.sciencedirect.com/science/article/pii/S266703132300091X

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