Stable reconstructed human gingiva–microbe interaction model: Differential response to commensals and pathogens

BackgroundTo investigate human oral health and disease, models are required which represent the interactions between the oral mucosa and microbiome. Our aim was to develop an organotypic model which maintains viability of both host and microbes for an extended period of time.MethodsReconstructed Hum...

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Bibliographic Details
Main Authors: Yan Zhang, Lin Shang, Sanne Roffel, Bastiaan P. Krom, Susan Gibbs, Dongmei Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.991128/full