Head-to-head comparison of diagnostic accuracy of four Ebola virus disease rapid diagnostic tests versus GeneXpert® in eastern Democratic Republic of the Congo outbreaks: a prospective observational studyResearch in context

Head-to-head comparison of diagnostic accuracy of four Ebola virus disease rapid diagnostic tests versus GeneXpert® in eastern Democratic Republic of the Congo outbreaks: a prospective observational studyResearch in context

Summary: Background: Ebola virus disease (EVD) outbreaks have emerged in Central and West Africa. EVD diagnosis relies principally on RT-PCR testing with GeneXpert®, which has logistical and cost restrictions at the peripheral level of the health system. Rapid diagnostic tests (RDTs) would offer a...

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Bibliographic Details
Main Authors: Daniel Mukadi-Bamuleka, Junior Bulabula-Penge, Bart K.M. Jacobs, Anja De Weggheleire, François Edidi-Atani, Fabrice Mambu-Mbika, Anaïs Legand, John D. Klena, Peter N. Fonjungo, Placide Mbala-Kingebeni, Sheila Makiala-Mandanda, Masahiro Kajihara, Ayato Takada, Joel M. Montgomery, Pierre Formenty, Jean-Jacques Muyembe-Tamfum, Kevin K. Ariën, Johan van Griensven, Steve Ahuka-Mundeke, Hgo Kavunga-Membo, Elie Ishara-Nshombo, Stijn Roge, Noella Mulopo-Mukanya, Espérance Tsiwedi-Tsilabia, Emile Muhindo-Milonde, Marie-Anne Kavira-Muhindo, Maria E. Morales-Betoulle, Antoine Nkuba-Ndaye
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:EBioMedicine
Subjects:
EVD
EBOV
GeneXpert
RDT sensitivity
Specificity
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423001330

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http://www.sciencedirect.com/science/article/pii/S2352396423001330

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