Direct structure determination of vemurafenib polymorphism from compact spherulites using 3D electron diffraction

The spherulite morphology is common among crystalline materials and melt-crystallized products, however, the structural determination of spherulites by X-ray diffraction remains difficult due to their polycrystalline nature. Here, the authors report the direct structure determination of the polymorp...

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Bibliographic Details
Main Authors: Shuting Li, Molly Lightowler, Xiao Ou, Siyong Huang, Yifan Jiang, Xizhen Li, Xiaodong Zou, Hongyi Xu, Ming Lu
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-022-00804-2