Production and evaluation of a recombinant chimeric vaccine against clostridium botulinum neurotoxin types C and D.

Bovine botulism is a fatal disease that is caused by botulinum neurotoxins (BoNTs) produced by Clostridium botulinum serotypes C and D and that causes great economic losses, with nearly 100% lethality during outbreaks. It has also been considered a potential source of human food-borne illness in man...

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Main Authors: Luciana A F Gil, Carlos Eduardo P da Cunha, Gustavo M S G Moreira, Felipe M Salvarani, Ronnie A Assis, Francisco Carlos F Lobato, Marcelo Mendonça, Odir A Dellagostin, Fabricio R Conceição
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3729698?pdf=render